During multi-slice interactive visualization for out-of-core seismic volume on common computing platform, traditional cache scheduling approaches, which take no account of the spacial relationship between blocks and slices, lead to the low cache hit rate while interacting. And it's also difficult to achieve high rendering quality by use of common multi-resolution rendering methods. In view of these problems, a cache scheduling strategy named Maximum Distance First Out (MDFO) was designed. Firstly, according to the spatial position of the interactive slice, the scheduling priority of the block in the cache was improved, which ensures that the candidate block has a higher hit rate when the slice interacts continuously. Then, a two-stage slice interaction method was proposed. By using the fixed resolution body block to ensure the real-time interaction, the final display quality was improved by the step-by-step refinement, and the information entropy of the block data was further combined to enhance the resolution of the user's region of interest. The experimental results show that the proposed method can effectively improve the overall hit rate of the body block and reach the proportion of more than 60%. Meanwhile, the two-stage strategy can achieve higher quality images for application-oriented requirements and resolve the contradiction between interaction efficiency and rendering quality for out-of-core seismic data visualization.